<form id="myForm">
    <input type="file" id="u_photo" name="u_photo" />
    <input type="button" id="submit-btn" value="上传" />
</form>

$("#submit-btn").on('click', function() {
    $.ajax({
        url:"/test/upload",
        type:"post",
        data:new FormData($("#myForm").get(0)),
        //十分重要，不能省略
        cache: false,
        processData: false,
        contentType: false,
        success: function () {
            alert("上传成功！");
        }
    });
});

$('#u_photo').on('change', function() {
    var file = this.files[0];
    if (file.size > 1024*1000) {
        alert('文件最大1M！')
    }
});

xhr: function() {
    var myXhr = $.ajaxSettings.xhr();
    if (myXhr.upload) {
        myXhr.upload.addEventListener('progress', function(e) {
            if (e.lengthComputable) {
                $('progress').attr({
                    value: e.loaded,
                    max: e.total,
                });
            }
        } , false);
    }
    return myXhr;
}

<dependency>
    <groupId>commons-io</groupId>
    <artifactId>commons-io</artifactId>
    <version>2.5</version>
</dependency>
<dependency>
    <groupId>commons-fileupload</groupId>
    <artifactId>commons-fileupload</artifactId>
    <version>1.3.2</version>
</dependency>

<bean id="multipartResolver" class="org.springframework.web.multipart.commons.CommonsMultipartResolver" />

@RequestMapping(value="/test/upload",method = RequestMethod.POST)
@ResponseBody
public String upload(@RequestParam("u_photo") MultipartFile u_photo) {
    System.out.println("u_photo="+u_photo.getSize());
    return "ok";
}